Fighting Arthritis

London, Ontario (CSG) -- Trixsyn's proprietary hyaluronan formulation helps maintain healthy joints. That is the conclusion of a pilot study recently concluded here recently at the University of Western Ontario.

In the case of osteoarthritis, joint health can be assessed objectively by a histopathological grading and staging scale. The Osteoarthritis Research Society International Working Group has established an assessment system with metrics reflecting both the depth of the progression of osteoarthritis into articular cartilage and the extent of the surface of the cartilage that is involved.*

As can be seen in the accompanying photomicrographs, the effect of Trixsyn's proprietary hyaluronan formulation in a preclinical study was dramatic, preventing the progression of osteoarthritis into articular cartilage and preserving the surface of the cartilage as well.

Figure 1: Sagittal section of stifle joint of control animal administered saline after cranial cruciate ligament resection.

Figure 2: Sagittal section of stifle joint of experimental animal administered CSG's Trixsyn brand hyaluronan after cranial cruciate ligament resection.

 

 

            

                                    Saline                                                        Trixsyn ®
                                 (Sample 1)                                                    (Sample 2)

  

 

 Download an abstract of this study here.

* Pritzker, K.P.H. et al., Osteoarthritis and Cartilage 14, 13 (2006). Abstract.